What is Novonorm (repaglinide)?

Novonorm (repaglinide) is a drug used to lower blood sugar levels in people suffering from type 2 (non-insulin dependent) diabetes. It is used alone or with other drugs, a proper diet and regular exercise to reduce blood sugar levels.

Important Information

Novonorm helps control high blood sugar, and in the process, prevents nerve problems, blindness, kidney damage, heart attack, stroke and sexual problems. It however should not be used to treat people suffering from type 1 or insulin dependent diabetes.

Do inform your doctor about any prescription, non-prescription or over-the-counter medication before starting Novonorm as some ingredients in Novonorm can interact with these drugs to cause allergies or other problems.

You have to disclose your medical history to your doctor or pharmacist before using Novonorm, especially if you suffer from kidney or liver disease.

As you may experience dizziness, drowsiness or blurred vision because of extremely low or high blood sugar levels, don’t drive, use machinery or do any activity that requires alertness or clear vision till you know you can safely perform such activities.

Reduce your alcohol consumption while taking Novonorm as it can lead to low blood sugar.

As stress because of an infection, injury, fever or surgery can make it more difficult for your doctor to control your blood sugar; you have to consult your doctor if in stress so that necessary changes can be made to the treatment plan, blood sugar testing or medications.

Novonorm should be used in pregnancy only if needed as pregnancy may cause or worsen diabetes. You need your doctor’s guidance for managing your blood sugar levels when pregnant.

As it is not known if Novonorm passes into breast milk, and what affects it has on the nursing baby, it is better to not breast-feed while using Novonorm.

What should I know before taking Novovorm?

You have to carefully follow your doctor’s directions for stopping any old drug you were taking like chloropropamide and are now starting Novonorm.

Do follow your doctor’s medication treatment plan, exercise program and meal plan for quick and maximum effects from Novonorm.

Make it a point to regularly check your blood sugar levels and keep track of records by sharing with your doctor. This is important for your doctor to regulate the right dosage required to control your blood sugar levels.

Do inform your doctor if your sugar levels are too high or low so that your treatment plan can be changed accordingly.


Repaglinide is the main ingredient found in Novonorm.

How it Works

Novonorm is an anti-diabetic medication used to lower the blood sugar levels in type 2 diabetics. It is used alone or with some other drug, regular exercise and a healthy diet to control blood sugar by stimulating the pancreas to produce more insulin.


Novonorm should be taken orally 15 minutes before your meal, usually 2-4 times a day depending on the number of meals you have and your blood sugar levels. Your doctor will prescribe the right dosage based on your health condition and how your body responds to the drug. However make sure you take Novonorm within half an hour o f having your meal and don’t take it if you skip a meal or if your blood sugar levels are low.


As any drug can cause drug interactions with Novonorm, you have to inform your doctor of any prescription, non-prescription and over-the-counter medication you take. Also inform your doctor if you smoke, use illegal drugs and frequently drink caffeinated and alcoholic drinks as it can affect the way Novonorm works.

Your doctor will prevent and manage interactions by changing your medications or with close monitoring. However do not start, stop or change the dosage of any medicine without your doctor’s approval.

Novonorm interacts with antibiotics, heart or blood pressure medicine, antifungal medications, HIV/AIDS medicines and NPH insulin. The other drugs that affect the removal of repaglinide from the body and affects its working include trimethoprim, cyclosporine, gemfibrozil, azole antifungal, macrolide antibiotics like erythromycin, St. John’s wort and rifamycins.

Some drugs like corticosteroids, psychiatric medicines and fluoroquinolone antibiotics like ciprofloxaxin may also affect your blood sugar levels, which only makes it more difficult to control your blood sugar.

Beta-blocker medications like propranolol and glaucoma eye drops like timolol can prevent the fast and pounding heartbeat you experience when your blood sugar levels fall low. Make sure you check labels of your cough and cold products as they may contain sugar or alcohol that affects your blood sugar levels.

Side effects of Novonorm (Repaglinide)

Like all drugs, Novonorm can cause some common side effects like nausea, dizziness, weight gain, blurred vision, diarrhea, back and joint pain or headache which you needn’t worry about. However if the condition persists or worsens, do notify your doctor or pharmacist.

Most people don’t suffer from any serious side effects because of repaglinide. However it can lead to low blood sugar or hypoglycemia, especially if you take other diabetic drugs. Even excessive consumption of alcohol, insufficient food and calories and doing too much of exercise can lead to low blood sugar.

These symptoms include cold sweat, chills, drowsiness, weakness, fainting, hunger, fast heartbeat, tingling of hands and feet and shaking. This is why it’s better to always carry glucose tablets or gel, or eat table sugar, candy, honey or a glass of fruit juice to treat hypoglycemia.

Symptoms of high blood sugar or hyperglycemia include confusion, drowsiness, rapid breathing, increased urination, flushing, thirst and fruity breath odor. If you experience any of these symptoms, inform your doctor immediately so that they can adjust your diabetes medication accordingly.

Not many people suffer from allergies after using Novonorm. However contact your doctor if you notice these symptoms:

  • Rashes, swelling and itching in the face, throat and tongue
  • Severe dizziness and breathing problems.

Frequently Asked Questions

What’s in Novovorm

Novonorm is an anti-diabetic medication used to lower blood sugar by stimulating the pancreas to produce more insulin. It is used with a healthy diet and regular exercise.

How does Novovorm work?

Novonorm works with at reducing blood sugar levels by stimulating the pancreas to produce more insulin, and is used with a healthy diet and regular exercise.

Are there any drugs I can’t take in combination with Novovorm?

While any drug can interact with the working of Novonorm, you shouldn’t take clarithromycin, dalfopristin, cyclosporine, delavirdine, erythromycin, diltiazem, fluconazole, ketoconazole, itraconazole, nicardipine, nifedipine, St. John’s wort, Phenobarbital and verapamil.

Can Novovorm cause an allergic reactions? If so, what are the signs?

Novonorm doesn’t usually cause allergic reactions. However do contact your doctor if you experience any rashes, swelling and itching in the face, throat and tongue, breathing difficulties and dizziness.